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Your CDMO for the next generation of breakthrough medicines

At Center for Breakthrough Medicines, our mission is to save lives by accelerating the development and manufacturing of advanced therapies.

Our fully integrated services include drug substance and drug product for all phases of the product lifecycle at a single site.

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Committed to saving lives together

The Center for Breakthrough Medicines (CBM) is uniquely positioned with the world’s largest single-site advanced therapies facility, located in the birthplace of cell and gene therapy and staffed by the most experienced depth of scientific talent in the industry.
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20+ Viral Vector Suites
20+ Cell Processing Suites
200 L GMP Plasmid Manufacturing
180+ Analytical Assays

Breakthrough ideas and recent events

Multi-Year Deal to Focus on Phase 3 Clinical Trial Supplies and Commercial Manufacturing King of Prussia, PA — September 20th, 2022 —The Center for Breakthrough Medicines (CBM), a contract development and manufacturing organization (CDMO) dedicated to addressing the unique requirements associated with commercializing cell and gene therapies, and jCyte, a clinical-stage biotech company focused on preserving and restoring vision in patients with retinitis pigmentosa (RP) and other retinal degenerative diseases, today announced a multi-year manufacturing agreement wherein CBM will be the primary manufacturer of jCyte’s U.S. Food & Drug Administration’s Regenerative Medicine Advanced Therapy (RMAT) designated cell therapy, jCell. Under the terms of the agreement, CBM will provide Phase 3 clinical trial supplies and commercial drug product following Biologics License Application (BLA) approval of jCyte’s proprietary jCell platform technology.  CBM will also provide all BLA-enabling Chemistry, Manufacturing and Controls (CMC) work to support the program through regulatory approval and commercialization. “jCyte is conducting truly advanced, groundbreaking research into treating patients with RP and other retinal degenerative diseases, and we are honored to partner with them during this critical phase of their clinical trial program as they prepare for BLA submission and commercialization,” said Joerg Ahlgrimm, Chief Executive Officer of Center for Breakthrough Medicines. “We have built world-class technical teams combined with industry-leading product and process development, manufacturing, and testing capabilities, all located within a single manufacturing facility. Our unique and focused approach simplifies and expedites the completion of critical product and process development work and subsequent manufacturing campaigns, thereby shortening the time to market entry

September 20, 2022

Join us in creating breakthrough therapies

CBM offers scientists the opportunity to work at the cutting edge of cell and gene therapy, developing breakthrough treatments.
You will work amongst the most experienced and talented people in the industry, including true pioneers of advanced therapies.
We are on a mission to be the world’s leading advanced therapy partner, and we want you to be part of our growth and success.
With a culture of empowerment and innovation, we will support you in creating new therapies that transform patients’ lives.

Life at CBM

Our empowering culture supports people committed to transforming patients’ lives.

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CBM is led by an amazing team. Discover the caliber of people you will work with.

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