Cell Banking
CONNECT WITH AN EXPERTIntegrated manufacturing of GMP cell and viral banks, and supporting characterization and release testing.
Services focused on ensuring the safety and longevity of critical biological starting materials
Cell and viral banks are a vital component for the manufacture of many gene & cell therapy products. It is critically important to ensure uniformity of the population, maintenance of cell integrity, and availability of sufficient material to support the entire lifecycle of the project.
Center for Breakthrough Medicines (CBM) offers clients the capability to manufacture GMP Master Cell Banks (MCB), Working Cell Banks (WCB), Master Viral Banks (MVB), and Working Viral Banks (WVB) as either a stand-alone service or in support of manufacturing campaigns. This production is fully integrated with characterization, release testing and stability studies at our single site, allowing for streamlined and accelerated availability of these critical starting materials.
Mammalian GMP Cell Banking
Master Cell Banks (MCB)
Working Cell Banks (WCB)
GMP Viral Banks
Master Viral Banks (MVB)
Working Viral Banks (WVB)
Viral Seed Stocks
GMP Microbial Cell Banking for Plasmid DNA
Master Cell Banks (MCB)
Working Cell Banks (WCB)
Double layer MCB and WCB for cell therapy
At CBM, we offer the industry-standard double layer cell banking system, comprising a Master Cell Bank (MCB) and production of a Working Cell Bank (WCB), which ensures customers have access to an inexhaustible supply of consistent cells. The cell banks are characterized and tested for contaminants in line with guidelines and subject to all best practices for handling, testing and storage – eliminating the number of times the cell line is handled, supporting your manufacturing process and regulatory submissions.
Master Viral Banks and Working Viral Banks
CBM also offers GMP production of Master Viral Banks (MVB) and Working Viral Banks (WVB) in support of viral-based products or production systems. This can be offered as a stand-alone service or in support of manufacturing campaigns at CBM. Our expert team and expansive campus allows for segregated buildings dedicated to virus manufacturing to ensure no cross-contamination. Colocation of viral cell banking services with the broader manufacturing services and the necessary testing allows for streamlined execution of manufacturing campaigns with coordinated timelines for the readiness of these critical starting materials.
Contact us to discuss how CBM’s integrated capabilities can support your program
Viral Vector Manufacturing
CBM’s viral vector capabilities efficiently and consistently delivers high yields in AAV, Lentivirus, HSV and Adenovirus vectors, accelerating the development of new therapies.
Cell Therapy Manufacturing
CBM has one of cell therapy’s most experienced teams and the largest single site facility in the industry. There is no greater centralization of expertise.
Our Experienced Team
Our team brings a wealth of experience from biopharma and advanced therapy CDMOs, ensuring that there is no safer place for your product.