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Achilles Therapeutics Expands UK and U.S. Manufacturing Capabilities

April 24, 2022

“Achilles Therapeutics plc, a clinical-stage biopharmaceutical company developing precision T cell therapies to treat solid tumors, is expanding its clinical manufacturing in the United Kingdom and the United States.

Achilles’ manufacturing facility at the Cell & Gene Therapy Catapult (Catapult) in Stevenage, UK, has received a manufacturing license from the Medicines and Healthcare products Regulatory Agency (MHRA) and, separately, the company has entered into a partnership agreement for clinical manufacturing with the Center for Breakthrough Medicines (CBM), a contract development and manufacturing organization in King of Prussia, Pennsylvania.

The additional peak annual capacity of up to 600 doses of the company’s personalized clonal neoantigen-reactive T cell product candidates, known as cNeT, will support clinical manufacturing in the two ongoing Phase I/IIa CHIRON and THETIS clinical trials in non-small cell lung cancer and melanoma, respectively.”

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